reperfusion injury

Reperfusion injury occurs when blood supply returns to tissues after a period of reduced blood flow, often due to a blockage, such as in a heart attack or stroke. While restoring blood flow is essential for delivering oxygen and nutrients, it can paradoxically cause further damage. This happens because the sudden influx of oxygen can lead to the production of harmful molecules called free radicals, which can injure cells. Additionally, inflammation can increase, further harming the affected tissues. Understanding this process is vital for improving recovery strategies after ischemic events.