NK1 Receptor Antagonists

NK1 receptor antagonists are a class of medications that block the action of a substance called substance P, which is involved in transmitting pain and regulating mood. By inhibiting the NK1 receptor, these drugs can help reduce nausea and vomiting, especially related to chemotherapy, and have potential benefits in treating depression and anxiety. Commonly used NK1 receptor antagonists include aprepitant and rolapitant. They are often prescribed to improve the quality of life for patients undergoing cancer treatment or managing certain mood disorders.