Substance P

Substance P is a small protein, called a neuropeptide, that acts as a messenger in your nervous system. It plays a key role in transmitting pain signals from the site of injury or irritation to your brain. Besides pain, it also influences inflammation, mood, and other functions like nausea and vomiting. Substance P is released by nerve cells and can affect immune responses, making it important in both normal bodily functions and certain conditions like chronic pain or inflammation. Its activity helps your body respond to injury and stress, but excessive or abnormal activity can contribute to pain and inflammatory diseases.