5-HT3 Receptor Antagonists

5-HT3 receptor antagonists are a class of medications that block the action of serotonin, a chemical in the brain that can cause nausea and vomiting. These drugs are commonly used to prevent and treat nausea and vomiting, particularly in patients undergoing chemotherapy, surgery, or those experiencing certain gastrointestinal issues. By blocking the 5-HT3 receptors, they help reduce the signals that trigger the vomiting reflex. Examples of these medications include ondansetron and granisetron, which are often well-tolerated and effective in managing these symptoms.