neurofibrillary tangles
Neurofibrillary tangles are abnormal clumps of protein that form inside brain cells, primarily associated with neurodegenerative diseases like Alzheimer's. These tangles consist mainly of a protein called tau, which becomes tangled and disrupts the cell's structure and function. As these tangles accumulate, they interfere with communication between neurons and can lead to cell death. This process contributes to the cognitive decline and memory loss seen in affected individuals. Understanding neurofibrillary tangles is crucial for researching effective treatments and interventions for diseases that impact brain health.
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Neurofibrillary tangles are abnormal clusters of twisted protein fibers found inside brain cells, particularly in conditions like Alzheimer's disease. They form when a protein called tau, which normally helps maintain the structure of neurons, becomes unstable and collapses. This disruption interferes with the cell's function and can ultimately lead to cell death. The presence of neurofibrillary tangles is associated with cognitive decline and memory loss, making them an important focus in understanding and researching neurodegenerative diseases. Their formation is often linked to the progression of Alzheimer's and serves as a key indicator of the disease's severity.