Mcl-1 (Myeloid cell leukemia 1)

Mcl-1 (Myeloid cell leukemia 1) is a protein that plays a crucial role in regulating cell survival and death, especially in immune cells. It helps prevent programmed cell death, allowing cells to live longer, which is important for maintaining healthy immune responses. However, overexpression of Mcl-1 is often found in certain cancers, where it contributes to the cells' resistance to treatment by allowing them to evade death. Thus, Mcl-1 is a key focus in cancer research, as targeting it could enhance the effectiveness of therapies and help eliminate cancer cells.