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Myeloid cell leukemia 1

Myeloid cell leukemia 1 (MCL1) is a protein that helps regulate cell survival by inhibiting programmed cell death, or apoptosis. It belongs to the Bcl-2 family of proteins and is essential for the growth and maintenance of certain cells, especially in the immune system and blood cell development. In some cancers, including leukemia, MCL1 can be overproduced, allowing cancer cells to avoid dying and continue multiplying. Understanding and targeting MCL1 is important for developing therapies aimed at promoting cancer cell death and improving treatment outcomes.