matrix metalloproteinases (MMPs)

Matrix metalloproteinases (MMPs) are a group of enzymes in the body that break down proteins in the extracellular matrix, which is the structure surrounding cells. They play a vital role in normal processes like tissue growth, wound healing, and development. However, when their activity becomes unbalanced, MMPs can contribute to diseases such as arthritis, cancer, and heart disease by degrading healthy tissues or facilitating tumor spread. MMPs are tightly regulated by inhibitors to ensure proper tissue maintenance and repair, maintaining a delicate balance critical for health.