Histone demethylases

Histone demethylases are enzymes that modify histones, which are proteins that help package DNA in our cells. Think of them as "editors" that can remove specific chemical tags called methyl groups from histones. By doing this, they can change how tightly or loosely DNA is wrapped around histones, influencing gene expression. This means that histone demethylases play a crucial role in regulating which genes are turned on or off, affecting everything from development to responses to environmental changes, and are important in maintaining proper cellular function and health.