
glucose-6-phosphate dehydrogenase deficiency (G6PD)
Glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) is a genetic condition where the body lacks an enzyme called G6PD, crucial for protecting red blood cells from damage. Without this enzyme, certain triggers like infections, certain foods (like fava beans), or certain medications can lead to the destruction of red blood cells, causing hemolytic anemia. This can result in fatigue, jaundice, and other symptoms. It mainly affects males and is most common in people of African, Mediterranean, or Asian descent. Management involves avoiding known triggers and seeking medical care when symptoms arise.