Fragile X Premutation

Fragile X Premutation refers to a genetic condition related to the Fragile X syndrome, which affects cognitive development and is the most common inherited cause of intellectual disability. In individuals with the premutation, the FMR1 gene has an altered number of repeats (between 55 and 200) that can lead to certain health issues, such as anxiety, mood disorders, and potential fertility problems. While they typically do not show the severe developmental challenges associated with Fragile X syndrome, individuals with the premutation may pass on a full mutation to their children, which can result in the syndrome's effects.