Cyclophilin D

Cyclophilin D is a protein found in mitochondria, the energy-producing structures in our cells. It plays a vital role in regulating how cells respond to stress, particularly during situations that can lead to cell damage or death, such as lack of oxygen or toxins. Cyclophilin D is best known for its involvement in a process called the mitochondrial permeability transition, which can trigger cell death. Research has shown that it may be a potential target for treatments in various diseases, including neurodegenerative conditions and heart disease, by helping to protect cells from damage.