Cortical spreading depression

Cortical spreading depression (CSD) is a temporary wave of electrical activity in the brain that spreads across the cerebral cortex. It often results in a period of reduced brain activity, which can lead to visual disturbances, headaches, or even migraines. CSD is thought to play a role in the development of migraine and can be triggered by various factors like stress, certain foods, or hormonal changes. This phenomenon involves a complex interaction of neurons and surrounding cells, ultimately affecting how the brain processes information temporarily. Understanding CSD helps researchers study brain function and migraine treatments.