Chargaff's ratios

Chargaff's ratios refer to two key observations made by biochemist Erwin Chargaff about the DNA of living organisms. He found that in any given DNA molecule, the amount of adenine (A) always matches the amount of thymine (T), and the amount of cytosine (C) always matches the amount of guanine (G). This means that A=T and C=G. These pairings contribute to the DNA structure, helping to explain how genetic information is stored and replicated, and they laid the groundwork for understanding the double helix structure discovered later by Watson and Crick.