CAPS (cryopyrin-associated periodic syndromes)

Cryopyrin-associated periodic syndromes (CAPS) are a group of rare, inherited inflammatory disorders caused by mutations in a gene that affects the body's immune response. People with CAPS experience recurrent episodes of fever, skin rashes, joint pain, and other symptoms due to uncontrolled inflammation. These episodes can vary in severity and frequency, impacting daily life. CAPS is part of a broader category of diseases known as autoinflammatory syndromes, which occur without infection or autoimmune triggers. Treatments focus on reducing inflammation and managing symptoms, often with medications that target the immune system.