NLRP3

NLRP3 is a protein that acts as part of the immune system's defense mechanism. It helps the body recognize signs of infection, damage, or stress by forming a complex called the inflammasome. Once activated, NLRP3 triggers the release of substances that promote inflammation, helping to fight off threats. However, if NLRP3 becomes overactive or uncontrolled, it can lead to excessive inflammation, contributing to conditions like gout, rheumatoid arthritis, and certain neurodegenerative diseases. Understanding NLRP3 is important for developing treatments that regulate inflammation and improve health outcomes.