Bruton’s agammaglobulinemia

Bruton’s agammaglobulinemia is a rare genetic disorder that affects the immune system. It is caused by a mutation in a gene called BTK, leading to a lack of B cells, which are crucial for producing antibodies. Without antibodies, individuals have a severely weakened ability to fight infections. This condition typically presents in early childhood, and affected individuals are at high risk for recurrent bacterial infections. Treatment often involves regular injections of immunoglobulin (antibodies) to bolster the immune defense and prevent infections. Early diagnosis and management are essential for improving health outcomes.