B-cell deficiency

B-cell deficiency is a condition where the body produces too few or malfunctioning B cells, which are a type of white blood cell responsible for producing antibodies that fight infections. Without enough effective B cells, the immune system struggles to defend against bacterial and viral infections, leading to increased susceptibility and recurrent illnesses. This deficiency can be inherited or acquired due to illnesses, treatments, or other factors. Managing B-cell deficiency often involves treatments like immunoglobulin replacement therapy to supplement missing antibodies and protect against infections.