Beclin-1

Beclin-1 is a protein that plays a key role in the process of autophagy, which is how cells clean and recycle their components. It helps initiate the formation of autophagosomes—structures that envelop damaged or unnecessary cell parts for destruction and recycling. By regulating autophagy, Beclin-1 helps maintain cellular health, remove harmful materials, and adapt to stress. It is also involved in processes related to immune responses and cell survival. Dysfunction or reduced levels of Beclin-1 have been linked to various diseases, including cancer, neurodegenerative disorders, and infections, highlighting its importance in maintaining cellular homeostasis.