ATP13A2 (PARK9)

ATP13A2, also known as PARK9, is a gene associated with a rare genetic disorder that affects movement, known as Kufor-Rakeb syndrome. This syndrome leads to symptoms similar to Parkinson's disease, such as tremors and stiffness, usually starting in childhood or adolescence. The ATP13A2 protein helps manage cellular functions, including the removal of waste and toxins. When mutations occur in this gene, it disrupts these processes, leading to neurodegeneration. Understanding ATP13A2 is crucial for researching potential treatments for this and similar conditions that impact motor control and overall brain health.