Secondary Hyperparathyroidism

Secondary hyperparathyroidism occurs when the parathyroid glands, which control calcium levels in the blood, overproduce parathyroid hormone (PTH) because the body perceives low calcium levels or vitamin D deficiency. This often happens in chronic kidney disease, where the kidneys can't effectively remove phosphate or produce active vitamin D, leading to imbalances. Elevated PTH then causes bones to release calcium and phosphate into the blood, which can weaken bones and cause other health issues. It's a compensatory response aimed at maintaining calcium balance but can lead to bone disease if untreated.