Phosphoinositide 3-kinase (PI3K)

Phosphoinositide 3-kinase (PI3K) is an enzyme that plays a crucial role in how cells communicate and respond to their environment. It helps transmit signals from outside the cell—such as growth factors or hormones—to inside the cell, influencing processes like cell growth, division, survival, and metabolism. When activated, PI3K triggers a chain reaction that promotes cell health and function. Proper PI3K activity is essential for normal development, but when it's overactive or impaired, it can contribute to diseases like cancer or metabolic disorders.