monoamine oxidase A deficiency

Monoamine oxidase A (MAO-A) deficiency is a rare genetic condition where the body lacks an enzyme that breaks down certain neurotransmitters, such as serotonin, norepinephrine, and dopamine. These chemicals play key roles in mood regulation and brain function. The deficiency can lead to symptoms like mood disorders, aggressive behavior, and heightened emotional responses. Individuals may also experience issues with anxiety and impulsivity. MAO-A deficiency is associated with mutations in the MAOA gene and can manifest in childhood, requiring careful management and support to address behavioral and psychological challenges.