MITF

MITF, or Microphthalmia-associated transcription factor, is a protein that plays a crucial role in the development of various cell types, including melanocytes, which are responsible for pigment in the skin, hair, and eyes. It regulates genes involved in pigmentation and is also important for the function of other cells, like those in the immune system. Mutations in the MITF gene can lead to conditions like hearing loss, skin abnormalities, and eye problems, highlighting its significance in human health and development. In research, understanding MITF helps in studying pigmentation disorders and certain cancers.