Image for HLA-B27

HLA-B27

HLA-B27 is a specific protein found on the surface of cells that plays a role in the immune system. It helps the body identify and fight infections. Certain people with HLA-B27 have an increased risk of developing autoimmune diseases, such as ankylosing spondylitis, which causes inflammation in the spine and joints. While having this protein doesn’t guarantee someone will get these diseases, it is a genetic marker that doctors may use to help diagnose certain conditions. Understanding HLA-B27 can aid in managing health, especially for those with unexplained joint or back pain.