fibroblast growth factor receptor 3 (FGFR3)

Fibroblast growth factor receptor 3 (FGFR3) is a protein located on the surface of cells and plays a crucial role in regulating cell growth and division. It is particularly important in bone development and growth. Mutations in the FGFR3 gene can lead to various conditions, such as achondroplasia, a common form of dwarfism characterized by short stature and skeletal abnormalities. FGFR3 acts as a gatekeeper, signaling cells to stop growing when they should, which is essential for maintaining proper bone structure. Understanding FGFR3 helps researchers develop treatments for related genetic disorders.