Factor V Leiden

Factor V Leiden is a genetic change that affects a protein involved in blood clotting. Normally, this protein helps regulate clot formation, preventing excessive clotting. In people with this mutation, the protein is less effectively controlled, increasing the risk of forming abnormal blood clots, especially in veins. While many with Factor V Leiden never develop clots, it can raise the risk for conditions like deep vein thrombosis or pulmonary embolism, especially if combined with other risk factors. It's inherited, meaning it runs in families, and can be diagnosed through blood tests.