endothelium-derived relaxing factor

Endothelium-derived relaxing factor (EDRF) is a substance produced by the endothelium, which is the thin layer of cells lining blood vessels. EDRF plays a crucial role in regulating blood flow by signaling the smooth muscles in blood vessel walls to relax. This relaxation allows blood vessels to widen, reducing blood pressure and increasing blood circulation. One of the main components of EDRF is nitric oxide, a gas that acts as a messenger in the body. Overall, EDRF helps maintain healthy cardiovascular function and is important for proper blood circulation.