Calcium-induced calcium release

Calcium-induced calcium release (CICR) is a process in cells where an initial influx of calcium ions triggers the release of more calcium from internal storage, like the endoplasmic reticulum. This occurs when a small amount of calcium enters the cell, often through special channels during muscle contraction or nerve signaling. The released calcium amplifies the signal, leading to stronger contractions in muscles or enhanced communication between nerve cells. Essentially, CICR acts like a domino effect, where one event sets off a larger reaction, crucial for various bodily functions.