Brunner syndrome

Brunner syndrome is a rare genetic condition that primarily affects males and is linked to a mutation in the gene responsible for producing the enzyme monoamine oxidase A (MAOA). This enzyme plays a crucial role in breaking down neurotransmitters, such as serotonin and dopamine, in the brain. As a result, individuals with Brunner syndrome may exhibit aggressive behavior, impulsivity, and mood disorders. The condition is inherited in an X-linked manner, meaning it is typically passed down through the mother. Understanding this syndrome helps in recognizing the biological factors influencing behavior and the importance of genetic research in mental health.