Ataxia telangiectasia mutated (ATM)

Ataxia telangiectasia mutated (ATM) is a protein that plays a crucial role in detecting and repairing DNA damage, especially from breaks caused by stress or injury. It acts like a sensor and coordinator, activating repair processes to maintain genetic stability. When ATM is defective or absent, cells struggle to repair DNA properly, leading to increased risk of cancer and neurodegeneration. This dysfunction underlies the genetic disorder called ataxia-telangiectasia, characterized by movement difficulties, immune problems, and increased cancer susceptibility. ATM is essential for preserving cell health and preventing disease by ensuring the integrity of our genetic information.