ALK (Anaplastic Lymphoma Kinase)

Anaplastic lymphoma kinase (ALK) is a gene that provides instructions for making a protein involved in cell growth and development. In some cancers, especially certain types of lung cancer and lymphoma, ALK can become mutated or rearranged, leading to uncontrolled cell growth. This abnormal behavior can contribute to the development and progression of tumors. Scientists have developed targeted therapies to treat ALK-related cancers by inhibiting the activity of the abnormal ALK protein, helping to slow or stop cancer growth and improve patient outcomes.