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Adverse Remodeling

Adverse remodeling refers to the harmful changes that occur in the structure and function of tissues after an injury, stress, or disease. In the context of the heart, for instance, it can happen after a heart attack, where the heart muscle may thicken or dilate inappropriately, making it less effective at pumping blood. This process can lead to complications, such as heart failure. Essentially, adverse remodeling is the body's way of trying to heal or adapt, but often results in a negative impact on the affected organ's performance and health.