Aldosterone Antagonists

Aldosterone antagonists are medications that block the action of aldosterone, a hormone produced by the adrenal glands that helps regulate sodium and potassium balance, blood pressure, and fluid levels. By inhibiting aldosterone, these drugs reduce water and salt retention, lower blood pressure, and decrease strain on the heart and blood vessels. They are often used in conditions like heart failure, high blood pressure, and certain cases of hormone-related kidney issues. Examples include spironolactone and eplerenone. These medications require careful monitoring to prevent, for example, elevated potassium levels or other side effects.