Image for U4/U6 snRNP

U4/U6 snRNP

U4 and U6 snRNPs are specialized protein-RNA complexes involved in the process of splicing, which edits pre-messenger RNA (pre-mRNA) to produce mature mRNA for protein synthesis. They are parts of the spliceosome, a dynamic structure that removes non-coding sequences (introns) from pre-mRNA. U4 and U6 snRNPs work together, with U4 holding U6 inactive until needed. When splicing begins, U4 releases U6, allowing U6 to catalyze the cutting and joining steps that remove introns. These snRNPs are essential for accurate and efficient gene expression regulation.