TRPA (Transient Receptor Potential Ankyrin)

TRPA (Transient Receptor Potential Ankyrin) is a type of ion channel found in sensory nerve cells. It acts like a gate that opens in response to specific stimuli such as cold temperatures, chemicals, or irritants. When open, it allows calcium and other ions to enter the cell, triggering signals that the brain interprets as sensations like pain, cold, or discomfort. TRPA channels play a key role in detecting environmental irritants and warning us of potential harm, contributing to protective reflexes like coughing or withdrawal from harmful substances.