TNF receptor superfamily

The TNF receptor superfamily consists of a group of receptors on cell surfaces that respond to specific signals called tumor necrosis factors (TNFs). These signals help regulate immune responses, inflammation, cell growth, and survival. When TNFs bind to these receptors, they trigger internal processes that can lead to cell death, division, or activation. This system is vital for maintaining health by controlling how the immune system responds to threats and damaged cells. Dysfunction in these receptors can contribute to diseases like autoimmune disorders and cancer.