Thyroid Peroxidase (TPO)

Thyroid Peroxidase (TPO) is an enzyme found in the thyroid gland, which is located in your neck. It plays a crucial role in producing thyroid hormones (T3 and T4) by helping to incorporate iodine into the hormone molecules. These hormones regulate your metabolism, energy levels, and overall body functions. When the immune system mistakenly targets TPO, it can lead to thyroid conditions like Hashimoto’s thyroiditis or Graves’ disease, affecting hormone production. Testing for TPO antibodies helps diagnose autoimmune thyroid disorders, providing insight into whether the immune system is attacking the thyroid.