The Ferritin Paradox

The Ferritin Paradox refers to the complex role of ferritin, a protein that stores and releases iron in the body. Typically, high ferritin levels suggest good iron reserves, but paradoxically, they can also indicate inflammation or oxidative stress, which are harmful. Conversely, low ferritin indicates iron deficiency and potential anemia. This paradox makes it challenging to interpret ferritin levels solely as a marker of health, because elevated levels can either mean adequate iron or underlying inflammation, complicating diagnosis and treatment decisions related to iron status.