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Tertiary hyperparathyroidism

Tertiary hyperparathyroidism occurs when the parathyroid glands—tiny glands in your neck that regulate calcium—become overactive, usually after long-term kidney disease. Normally, when calcium levels are low, these glands release more hormone to raise calcium. In chronic kidney disease, the glands stay overactive even when calcium levels return to normal or become high, leading to excessive calcium release. This can cause symptoms like weak bones, fatigue, and abdominal issues. It often requires medical treatment, which may include medications or surgery to remove the overactive glands.