SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)

SMARCA4 is a gene that produces a protein involved in controlling how DNA is packaged inside our cells. This protein is part of a larger complex called SWI/SNF, which helps switch genes on or off by remodeling chromatin— the structure that organizes DNA. Proper functioning of SMARCA4 is essential for processes like cell growth and development. Mutations or malfunctions in SMARCA4 can lead to problems, including increased risk of certain cancers, because they disrupt normal gene regulation and cell behavior.