SHH medulloblastoma

SHH medulloblastoma is a type of brain tumor that develops in the cerebellum, the part of the brain responsible for coordination and balance. It originates from abnormal cells in the Sonic Hedgehog (SHH) signaling pathway, which normally helps regulate cell growth during brain development. This subtype is more common in infants and adults. Symptoms can include headaches, nausea, balance issues, and coordination problems. Treatment typically involves surgery, radiation, and chemotherapy. Advances in understanding its molecular features have improved diagnosis and targeted therapies, leading to better management and outcomes for patients.