
Sequencing by synthesis
Sequencing by synthesis is a method used to determine the order of bases (A, T, C, G) in a DNA molecule. It works by repeatedly adding nucleotides to a DNA strand while detecting which ones are incorporated. As each nucleotide is added, special sensors identify the specific base based on emitted signals. This process builds the DNA sequence step-by-step, allowing scientists to read the entire genetic code accurately and efficiently. It's the core technology behind many modern DNA sequencing platforms, enabling detailed genetic analysis crucial for research, medicine, and biotechnology.