RPE65 Protein

RPE65 is a protein found in the retina, the light-sensitive layer at the back of the eye. It plays a crucial role in the visual cycle, which is the process that helps convert light into signals the brain can understand as images. Specifically, RPE65 helps regenerate a molecule called retinal, which is essential for vision. Mutations in the RPE65 gene can lead to vision problems or diseases like Lebers congenital amaurosis, causing severe vision impairment or blindness. Understanding RPE65 has led to gene therapy advancements, offering hope for treatments for certain inherited retinal disorders.