Rho GTPases

Rho GTPases are proteins inside cells that act like molecular switches, controlling the cell's shape, movement, and organization. They help coordinate processes such as cell migration, growth, and division by signaling the cell's interior to reorganize its skeleton and adapt to its environment. These proteins cycle between an active state (on) and an inactive state (off), regulating various dynamic activities essential for normal cell function and development. Proper regulation of Rho GTPases is vital; their misregulation can contribute to diseases like cancer and developmental disorders.