Rho GTPase family

The Rho GTPase family consists of proteins that act like molecular switches inside cells, controlling critical functions such as shaping the cell’s structure, movement, and communication. They toggle between active and inactive states, regulating processes like the formation of the cell’s internal skeleton (cytoskeleton), cell migration, and signaling pathways. Rho GTPases are essential for normal cell behavior and development, and their malfunction can contribute to diseases like cancer. They play a key role in coordinating how cells respond to their environment and maintain proper function.