Rho GTPase

Rho GTPases are a family of proteins that act as molecular switches inside cells, controlling essential functions like cell shape, movement, and the organization of internal structures. They cycle between active and inactive states, regulating processes such as cell migration, growth, and division. By influencing the actin cytoskeleton—the cell’s framework—they help cells respond to their environment and maintain proper function. Rho GTPases are critical for normal development and immune responses, and their malfunction can contribute to diseases like cancer and neurological disorders.