pufferfish toxin

Pufferfish toxin, known as tetrodotoxin, is a potent natural substance that blocks nerve signals, leading to paralysis. Found mainly in the fish's skin, liver, and gonads, it prevents nerves from transmitting messages to muscles. If ingested, even a small amount can cause numbness, dizziness, difficulty breathing, and can be fatal if not treated promptly. Despite its danger, some cultures have developed careful preparation methods to safely consume pufferfish, such as fugu in Japan. The toxin is highly specific and potent, making pufferfish a fascinating yet risky delicacy.