Protease-activated receptors (PARs)

Protease-activated receptors (PARs) are a type of cell receptor that respond to enzymes called proteases, which break down proteins. When proteases activate PARs by cutting on their surface, it triggers a signal inside the cell, influencing processes like inflammation, blood clotting, and pain. These receptors act as sensors, helping cells detect and respond to changes in their environment, especially during injury or infection. PARs play a crucial role in maintaining bodily functions and responding to damage or threats, and their activity is tightly regulated to prevent excessive responses.