Pearson syndrome

Pearson syndrome is a rare genetic disorder caused by mutations in mitochondrial DNA, affecting the energy-producing parts of cells. It primarily impacts the bone marrow and the pancreas, leading to anemia (low red blood cells) and difficulty digesting food. Symptoms often start in infancy and can include fatigue, weakness, and poor growth. The severity varies; some may experience severe complications, including kidney or liver problems. As a mitochondrial disorder, it results from problems in the cells' energy production, impacting multiple organs. While there is no cure, treatment focuses on managing symptoms and supporting affected organs.